This is the VOA Special English Development Report. The World Health Organization is employing a new combination of drugs to treat human African trypanosomiasis illness, also recognized as sleeping sickness. The drugs nifurtimox and eflornithine will be given out in Uganda and the Democratic Republic of Congo. Officials from the Drugs for Neglected Diseases Initiative say the new treatment has fewer side effects. It is also much more powerful and much less expensive than the drugs traditionally used. In addition, the new treatment reduces the number of injections required. And it shortens the amount of time patients need to spend in the hospital. Sleeping sickness threatens millions of men and women in thirty-six countries in Africa. Most live in poor rural areas. The illness is caused by the trypanosoma parasite. It is spread to humans by means of the bite of infected tsetse flies. Widespread signs of sleeping sickness consist of fever, headaches, extreme tiredness and pain in the muscles and joints. Early identification of the illness may be difficult since several infected folks do not show any immediate symptoms. Over time, the parasites invade the central nervous system. The disease causes sleep disorders, mental confusion, personality changes, speech difficulties, seizures and coma. If left untreated, sleeping sickness kills. The World Health Organization estimates that about sixty thousand individuals are currently infected with the disease. It develops in two diverse forms. Trypanosoma gambiense is responsible for ...
Video Rating: four / five
Sunday, April 17, 2011
New Treatment for Sleeping Sickness
Tuesday, March 29, 2011
Are Your Blood Pressure Meds Making You Sick?
Post by Don Penven
Blood pressure medicines are offered only by prescription. Why not over the counter? Just because they are hazardous drugs and their use must be monitored by a physician. Just how dangerous are they? Here are some of the side-effects: fluid retention, nausea, diarrhea, leg cramps, skin rashes, impotence, extreme tiredness, weakness, insomnia, headache, low potassium levels, lack of sleep and frequent urination. According to the National Institutes of Health (NIH), high blood pressure can affect all kinds of men and women. People have a greater risk of HBP if they have a family history of the illness. HBP is more typical in African Americans than Caucasians, and old age is a factor too. Among the other risk factors leading to HBP are smoking, alcohol consumption, obesity and diabetes.
Most of the time, no cause is identified. This is referred to as essential hypertension. HBP that outcomes from a distinct condition, habit or medication is referred to as secondary hypertension. Diets that incorporate excessive salt are a enormous contributing factor.
A little over 40 years ago, as I was in the middle of an insurance exam, my physician told me I had high blood pressure. Say What? I'm only 30 years old.
So what can a person do? Follow his doctor's advice. Commence a regimen of medications that won't cure it-just maintain it under control--sometimes. So for all those years I've been on some costly drugs that have consistently helped to taint the city waste treatment treatment plant wherever I was living at the time.
The NIH states that blood pressure readings are measured in millimeters of mercury (mmHg) and normally given as two numbers. For example, 120 over 80 (written as 120/80 mmHg). The leading number is your systolic pressure, the pressure produced when your heart beats. It is regarded as high if it is consistently over 140. The bottom number is your diastolic pressure, the pressure inside blood vessels when the heart is at rest. It is regarded as high if it is consistently over 90.
Either or both of these numbers could be too high.Pre-hypertension is when your systolic blood pressure is between 120 and 139 or your diastolic blood pressure is between 80 and 89 on several readings. If you have pre-hypertension, you are far more likely to develop high blood pressure.
Your physician may also tell you to physical exercise, lose weight, and follow a healthier diet. If you have pre-hypertension, your doctor will suggest the very same way of life changes to bring your blood pressure down to a regular range.
Typically, a single blood pressure drug might not be enough to control your blood pressure, and you might be told to take two or a lot more drugs. It is really crucial that you take the medications prescribed to you. If you have side effects, your wellness care provider can substitute a distinct medication. (It's like chasing your tail-around and around we go.)
Some of the most commonly prescribed drugs include: Alpha blockers, Angiotensin-converting enzyme (ACE) inhibitors, Angiotensin receptor blockers (ARBs), Beta-blockers, Calcium channel blockers, Central alpha agonists and Diuretics.
This is where I ended up. Just a short time ago I was taking an ACE inhibiter, beta blocker, diuretic and a statin (to control high cholesterol).
Over time, and diverse doctors with distinct favorites, I've been prescribed a dozen or much more diverse types and various brands. And I was no better off than I was 40 years ago. And I haven't mentioned heart disease.
The Mayo Clinic concurs with the NIH in its list of risk elements and side effects, and it also points out that numerous youngsters, especially those who are overweight, are also at risk for creating hypertension. They even go as far to state that for a growing number of youngsters, poor way of life habits - such as an unhealthy diet and lack of exercise - contribute to high blood pressure.
A nationally identified wellness researcher, Christian Goodman Author of Natural Health Alternatives states, "It is a nicely-recognized truth that hypertension medications cause severe side effects. Even the medical companies have to admit to that. But to defend themselves, they say: "No efficacy with out side effects". Goodman goes on to say that hypertension medications neither cure hypertension nor protect you from sudden fatal cardiovascular events - such as heart attack, stroke, embolism, kidney failure and other conditions that are directly caused by high blood pressure. It frequently doesn't even work to normalize the blood pressure itself.
So what's a person to do? Well, even the NIH casually admits that there are option treatments but provides small detail. If you are taking any of those meds listed above, it is a crap-shoot that they aren't slowly making other well being difficulties. If you are the least bit curious about what alternatives are accessible, then request the unique report listed below. It could save your life!
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About the Author
Don Penven is a freelance writer and professional photographer with locations in Raleigh and Morehead City, NC. He was 1st diagnosed with hypertension over 40 years ago.
A film made for the Wellcome Trust on the history of study into trypanosomiasis. Traces the history of the illness from the 14th. to the 19th. century and consists of much historical material. Discover out far more: catalogue.wellcome.ac.uk
Video Rating: five / five
What Causes Sleep Deprivation and How to Deal with It?
Post by Tauqeer Hassan
If one is worried about suffering from sleep deprivation then one will absolutely wonder why it happens. Over twenty five percent of American population is affected by sleep deprivation. Sleep deprivation cam make 1 feel lazy, much less energetic, tired, fatigued, irritable, sensitive and even depressed. The brain, digestive organs and immune systems are also harmed by sleep deprivation that is a cause of significant symptoms. Sleep deprivation effects are widespread and can be affecting the body and mind a lot more than one thinks.
The question is that what causes this and why is sleep so significantly critical. Sleep causes the body to recharge at night. The body gets a opportunity to revive and fight off illnesses even though sleeping. The brain gets a opportunity to relax and remain anxiety totally free. The body will not function correctly without having sleep simply because the body and brain wants rest in routine lives. Sleep should be for at least seven to eight hours to be able to work productively and stay awake.
If the brain is not given a chance to sleep for a excellent amount of time every night, this will result the chemicals to turn out to be imbalanced. This will not be great and this imbalance will not let the person believe clearly and make wise decisions. This will also trigger the person to turn into a lot more emotional and angered simply. Those people who suffer from sleep deprivation may possibly end up depressed as they are not able to handle their emotions and anxiety because of their lack of sleep.
Sleep affects the body since the organs particularly the immune system needs a chance to refresh because of the truth that they can not work difficult in the course of the day with several activities going on every single minute. Sleep deprivation can substantially make the immune system weak and can cause one to grow to be sick frequently for a longer time. The immune system can not work appropriately without relax time of sleeping. It is very critical to have appropriate sleep every night and even much more sleep in case of sickness. It is feasible that an individual may not feel sleepy at one time of day but might expertise a sudden onset of totally disabling drowsiness when all stimulating influences are withdrawn.
The causes of sleep deprivation are both voluntary and involuntary. Individuals often basically ignore the sleep which is necessary but at other times, the body is not capable of getting needed hours of sleep each night simply because of illness or other reasons. Besides adults, teens and college students, sleep deprivation can be even found in babies effects of sleep deprivation on babies and young children are a real difficulty for their mental, physical and emotional development.
The digestive system also suffers from lack of sleep and the glucose metabolism is affected. The glucose will be unable to process although the body will be affected by it significantly. This can result in diabetes or other wellness problems. Not only the effects of sleep deprivation take a mental toll on the body but they also affect a individual physically and emotionally. Individuals with sleep deprivation need to not feel that a couple days of rest will solve the problem due to the fact it will not. The body requires continuous ongoing rest to function properly on a daily basis.
The human body is naturally created to have appropriate time for rest and sleep, this is the reason there are nights. 1 should wisely manage the time to have appropriate sleep each day. It is component of creation and it doesn't matter what one believes religiously or not even believe in religion. In truth every single person who is born in this world has to sleep and there is no reason why a individual need to not. Each and every day has twenty four hours 1 need to plan the time accordingly to have a appropriate sleep. Sleeping is very good for health and makes 1 feels psychologically and physically significantly much better. Finding enough sleep by sleeping all through the night is 1 of the essentials to becoming emotionally, mentally and physically healthy.
About the Author
Also understand why does sleep deprivation occur and why does old aspirin smell like vinegar?
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What African Trypanosomiasis Is All About
Write-up by D Chosen 1
Trypanosomiasis is differentiated into the African Trypanosomiasis and the American trypanosomiasis (Chigas' Disease) which are prevelent in the respective regions bearing their names. It is a transmissible illness conveyed by bites of tse tse fly and hence a good information of such a illness can equip 1 for adequate prevention
African TrypanosomiasisThe causative agents for the African Trypanosomiasis (sleeping sickness) are the Trypanosoma brucei gambiense and Trypanosoma brucei rhodesiense. Both forms are transmitted by the bite of infected tsetse flies (Glossina species), which inhabit the open savannah of eastern Africa (T.b.rhodesiense) or riverine areas in western and central Africa (T.b.gambiense). Wild game mammals (hartebeest, lion, hyena) as properly as cattle act as reservoirs of T.b.rhodesiense. Trypanosoma b.gambiense has been found mostly in domestic pigs, cattle, and dogs. Though, there is evidence that antelope may also carry the parasite. Numerous fly-man transmission are far more widespread in west and central Africa. When the trypanosomes are ingested by tsetse fly they embark on a complex cycle of development and multiplication, initial in the fly's gut and later in its salivary glands.
<u>Morphology</u>Trypanosoma b.gambiense can be observed as spindle-shaped cells with an undulatory membrane and pointed flagella at the ends. The organisms are motile, 25-40 micrometer in length. Their cytoplasm is stained light-blue although the nucleus, blepharoplast and flagellum are stained red.
<u>Pathogenesis and clinical manifestations</u>Trypanosomiasis is a transmissible disease and is covered by the bite of the tsetse flies. Infection with trypanosomes gives rise to African sleeping sickness which is characterized by fever, rash, headache, lymphadenopathy, Odema of the brain. T.b.rhodesiense is far more virulent. Rhodesien form of trypanosomiasis develops inside weeks to months. Gambian form develops within years. The disease becomes chronic and persists for months and even years. There are alternating periods of fever and apparent recovery, followed by depression and progressive lethargy. A slight number of parasites are present in the blood. The trypanosomes are present in the tissues, particularly in the muscles and in the cerebrospinal fluid. The patient dies regularly from the disease.
<u>Laboratory diagnosis</u>It comprises of microscopic examination of blood and material obtained by puncture of the enlarged lymph nodes examination of the cerebrospinal fluid (for the presence of trypanosomes).
Prophylaxis is ensured by a complex measures which contain recognition and treatment of patients, protection of the population from the bites of tsetse flies (Glossina palpalis), the use of insect repellents, extermination of vector flies.
Trypanosoma CruziThis is the causative agent of the American trypanosomiasis (Chigas' Disease). T. cruzi was discovered in 1909 by C. Chigas in Brazil. Children are the most susceptible to this illness. American trypanosomiasis is transmitted by bite of different bug species of the family members Triatomidae. The natural reservoirs of the disease are wild animals- armadilloes, opossums, rodents, and monkeys.
<u>Clinical manifestations</u>Children younger than 1 year of age suffer from the illness extremely frequently and die inside a couple of days. In adults, the disease is accompanied with a rise of temperature, edema of the face, and enlargement of the thyroid gland lymph nodes, spleen and liver.
<u>Laboratory diagnosis</u>This is created by examinations of patient's blood guinea pig inoculation with 5-10ml of patient's blood. Prophylaxis is achieved by extermination of bugs (the vectors of the causative agent). Chemoprophylaxis with unique preparation is carried out in endemic areas.
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what if i had trypanasoma brucei gambiense Info and pics from Berger, Jürgen and Overath, Dr. Peter,February 4, 2003 100 (three) Proceedings of the National Academy of Sciences On the internet, www.pnas.org Bosley, sarah. Friday May possibly 15, 1985,http//www.guardian.co. uk/science/2004/may15/sleeping-sickness-treatment-africa-breakthroughs. Wikipedia, CDC.com, Zimmer, Carl. Parasite Rex:Inside the Bizzare World of Natures Most Hazardous Creatures,Touchstone, Rockefeller Center New York, NY. 2001.
Biomed Analysis: Eliminating sleeping sickness for good
Once again we are close to eliminating sleeping sickness, or human African trypanosomiasis — a disease discovered a century ago.
Read more on SciDev.net
FDA approves ipilimumab for metastatic melanoma treatment
The U.S. Food and Drug Administration announced nowadays its approval of a new treatment for advanced melanoma, the deadliest and most tough-to-treat form of skin cancer.
Read much more on News-Medical-Net
What Causes Joint Pain And Arthritis Knee Pain?
Article by Mike Trudeau
There are a lot of causes of joint pain arthritis knee pain, though the majority is from illnesses. Joint pain can also be felt from injuries, infections and some allergic reactions to medications. Treatment for joint pain will depend on the exclusive cause and scenario. You might require to have joint replacement surgery, need to switch medications, or just take immune suppressant's. Most joint discomfort is destructive and degenerative, so you could will need to change your activities or way of life to accommodate or uncover relief for the joint pain, depending on the severity.
Joint discomfort can be associated with discomfort, your nervous system, head symptoms, muscle symptoms, swelling, movement symptoms, skin symptoms, muscle weakness, fever, body temperature, stiffness, and fatigue. Some of these causes are very easy to treat whilst others cannot truly fix the cause, but allow you to function with the joint discomfort. Arthritis knee discomfort not only causes discomfort, but debilitation in some much more severe circumstances.
Viral infections, the typical cold, the flue and other bacterial infections all can cause joint discomfort. The numerous types of arthritis cause joint pain, from light discomfort to really sever and debilitating pain. The list of arthritic causes is extensive. Osteoarthritis, rheumatoid arthritis, juvenile rheumatoid arthritis, ankylosing spondylitis, rheumatism, Reiter's syndrome, psoriatic arthritis, gonococcal arthritis, and inflammatory bowel syndrome are widespread culprits.
Some other frequent causes for aching joints are African sleeping sickness, east African trypanosomiasis, optic neuropathy, anterior ischemic, and West African trypanosomiasis. Severe joint discomfort causes are avascular necrosis, bartonella infections, bertonellosis, haemoglobin S/haemoglobin Lepore, Boston, Hemoglobin S/haemoglobin ), Arab, and Hemoglobin SC. Charcot joint discomfort, which is the degeneration of a stress bearing joint, such as your knee, is caused by repeated trauma, chronic haemarthrosis, chondrocalcinosis, and rheumatoid arthritis.
Joint redness, joint discomfort, joint inflammation, joint swelling and other joint symptoms are all connected with arthritis. Some causes of arthritis are acrodysostosis, Behcet's disease, Blau syndrome, Caplan's illness, Ciproflaxin, Diffuse idiopathic skeletal hypertostosis, Escherichi coli, Farber's illness, Bone fracture, Hemophilia kind A, Hepatitis A, Kawasaki disease, Mayaro virus fever, Methimazole, mixed connective tissue disease, Mycoplasma pneumonia, obesity, PAPA syndrome, pituitary tumor, rheumatic fever, rubella, sickle cell disease, Streptococcus suis, raised Urid acid levels, West Nile fever, and Winchester. And that's just naming a few.
Gout related arthritis is a joint condition linked with the accumulation of urate crystals in the joints. It can be caused by familial juvenile hyperuricemic nephropathy, juvenile gout, Kelley-seegmiller syndrome, lesch-nyhan syndrome. Rheumatoid arthritis which causes quite sever joint pain is caused by cartilaginous deafness syndrome, chromosome 22q deletion, chromosome 22q11.2 deletion syndrome, felty syndrome, Hashimoto's thyroiditis, human adjuvant illness, hyperprolactinemia, significant granular lymphocyte leukaemia, systemic juvenile rheumatoid arthritis and X-linked agammaglobulinemia.
It is essential to remember that joint discomfort is a symptom of many distinct causes. You need to diagnose and recognize, rather than target the symptoms of joint pain. This will help in determining why you are experiencing the joint pain. Joint discomfort is commonly found in those 45 years of age and older. Most generally rest, exercise, massage, stretching and warm baths can efficiently treat nonarthritic joint discomfort. There are also anti-inflammatory medications that can relieve any swelling and inflammation. There is also unique physical therapy for muscle and joint rehabilitation. You may will need to have fluid removed from your joints to get rid of joint discomfort.
Without having a doubt joint discomfort plaques millions of people. In some cases treatments or medication are efficient in treating joint discomfort. In other cases a a lot more aggressive approach might be needed. Regardless, new developments and technologies are producing remedies far more and much more effective.
About the Author
If you have questions or are searching for what causes joint discomfort you can locate further details at the joint discomfort site. For additional details on arthritis knee discomfort and how it affects the joints that is covered as properly.
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Q&A: Motion Sickness from Video Games? PLEASE HELP!!?
I've been playing video games for years, and had in no way gotten motion sickness from them up until recently when I started playing first individual shooters. I play them for a couple of hours, (A couple is stretching it) and get so sick it's unbelievable. I've spent nights with out sleep due to the fact I've gotten so poor from it.
I've gotten new glasses, and that helped but I still get quite queasy. I do not sit in front of the television, and I've tried playing in both dark, and well lit rooms but absolutely nothing seems to decrease the motion sickness.
Have any of you had the identical difficulty, and how did you fix it? If not, what do you think would aid??
P.s. I figured I'd post this in the heath section since this is a lot more about my sickness then video games.
Finest answer:
Answer by Chris
Yes, truly I have also. I thought it was weird also, trigger I, like you have been playing video games for years and by no means had it happen. I personally just have been avoiding those games for the time being, but perhaps some dramamine would support.
Give your answer to this question below!
African Sleeping Sickness - A Medical Dictionary, Bibliography, and Annotated Research Guide to Internet References
African Sleeping Sickness - A Medical Dictionary, Bibliography, and Annotated Investigation Guide to Net ReferencesIn March 2001, the National Institutes of Health issued the following warning: "The number of Web sites offering wellness-related resources grows every single day. Many websites provide useful details, while others might have data that is unreliable or misleading." Furthermore, because of the rapid improve in Internet-based data, several hours can be wasted looking, choosing, and printing.This book was developed for medical professionals, students, and members of the general public who wan
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African sleeping sickness
Write-up by Sadia
African sleeping sickness is an epidemic which affects individuals mostly in Africa and all around the world. According to estimation of WHO this disease affects 25,000 men and women around the globe. How is African sleeping sickness spread?This illness spread via bite of Trypanosoma brucei infected tsetse fly. Its mode of spread is almost similar to the mode of spread of malaria. The tsetse flies are found typical in Africa. Moreover, it can spread from infected mothers to her baby. It can be transmitted via infected blood transfusion. Can African African sleeping sickness be lethal?Yes, it can be lethal, if it fails to obtain medical treatment. Death will be occurred in some weeks but in most of the instances patients will recover soon. What are the symptoms of African sleeping sickness?The primary symptoms of this disease consist of headaches, joint pains, and itching. If the infection invades in lymphatic and circulatory system, swelling of lymph nodes may happen. If it is left untouched, the illness can overcome the immunity of body and can trigger other extensive damages. This can affect crucial organs of body. In secondary stage, the infection invades in CNS which is referred to as the neurological phase. The word sleeping sickness is in fact depends on neurological phase. These symptoms incorporate confusion, disruption of sleep cycle and reduced coordination. How can we stop ourselves from African sleeping sickness? To stop your self from this illness, you really should You really should wear protective clothing like thick fabric and lengthy-sleeved shirts and pants. The tsetse fly can bite by way of thin fabrics, so you need to stay away from it. You ought to wear light colored clothing due to the fact these flies attracted to dark colors so steer clear of utilizing it. You ought to use insect repellant to stay away from insect biting. You need to use bed netting when sleeping.Be careful and live healthy.
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